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Field medications · Adult & pediatric guidance · ALS

Morphine sulfate

Adult formulation-dependent doses and pediatric weight-based analgesia.

OCEMS source summary · Updated 2026-09-16

Check before giving

  • Withhold if systolic BP is below 90 or falls below 90; adult injury/burn orders require BP above 90 before giving analgesia.
  • Morphine is stocked in different concentrations. A matching milligram dose can require a very different volume.

Use in OCEMS

  • Opioid analgesia for appropriate injury/burn pain and IV treatment of suspected cardiac pain after nitroglycerin fails or cannot be given.
  • I-15 retains different adult doses for the 4 mg carpuject and 10 mg/mL vial presentations.

Adult / adolescent

Indication / routeDose & limits
Pain — IV/IM4 mg from the 4 mg carpuject, or 5 mg with the 10 mg/mL vial. May repeat once after about 3 minutes for persistent pain.
Cardiac painUse the IV route under SO-C-015 after 3 nitroglycerin doses fail or nitroglycerin cannot be administered.
IO in crush/burn injuryOnly if already established for other treatment: 4 mg or 5 mg according to the preparation, with one repeat after 3 minutes as specified in I-15.

Pediatric

  • SO-P-015 severe injury pain: 0.1 mg/kg IV/IM, maximum 5 mg per dose. May repeat once after 3 minutes; total maximum 10 mg.
  • Contact base for children age 2 or younger under SO-P-015. Check the pediatric condition order before using an IO route.

Pediatric weight table — Severe injury pain

  • Source: SO-P-015. Dose rule: 0.1 mg/kg; route: IV/IM.
  • 0.1 mg/kg IV/IM, maximum 5 mg per dose. May repeat once after 3 minutes; total maximum 10 mg.
  • Base contact is required for age 2 or younger. Match the product concentration and route: the I-20 examples distinguish IV carpuject products from the 10 mg/mL IM preparation.
  • Calculated examples for the exact weights shown, using the named standing-order/procedure formula. Do not round the patient’s weight to the nearest row. For another weight, calculate from the stated formula and apply the limits. These are not the rounded I-20 weight-band volumes.
  • Volumes are mathematical examples rounded to at most three decimal places. Verify the vial concentration, dose, and measurable syringe volume before administration; follow agency preparation/rounding practice.
Exact weightDose — IV/IMVolume at 1 mg/mL — IVVolume at 4 mg/mL — IVVolume at 10 mg/mL — IM
3 kg0.3 mg0.3 mL0.075 mL0.03 mL
4 kg0.4 mg0.4 mL0.1 mL0.04 mL
5 kg0.5 mg0.5 mL0.125 mL0.05 mL
6 kg0.6 mg0.6 mL0.15 mL0.06 mL
8 kg0.8 mg0.8 mL0.2 mL0.08 mL
10 kg1 mg1 mL0.25 mL0.1 mL
12 kg1.2 mg1.2 mL0.3 mL0.12 mL
15 kg1.5 mg1.5 mL0.375 mL0.15 mL
20 kg2 mg2 mL0.5 mL0.2 mL
25 kg2.5 mg2.5 mL0.625 mL0.25 mL
30 kg3 mg3 mL0.75 mL0.3 mL
35 kg3.5 mg3.5 mL0.875 mL0.35 mL
40 kg4 mg4 mL1 mL0.4 mL
45 kg4.5 mg4.5 mL1.125 mL0.45 mL
50 kg5 mg5 mL1.25 mL0.5 mL
60 kg5 mg5 mL1.25 mL0.5 mL

Preparation & reassessment

  • Confirm the concentration on the actual vial/syringe and record total milligrams.
  • Reassess pain, respiratory effort, mental status, and blood pressure. Document dose times and response; maintain readiness for airway support.