Field medications · Adult & pediatric guidance · BLS / ALS
DuoDote (atropine / pralidoxime)
Combination auto-injector for organophosphate/nerve-agent toxicity, with age and weight restrictions.
OCEMS source summary · Updated 2026-09-16
Check before giving
For patients older than 65, B-035 requires weight of at least 80 kg to receive an auto-injector.
Do not exceed 3 devices unless definitive medical care is available. Ensure scene safety and move to a safe area when possible.
Use in OCEMS
For possible/known organophosphate insecticide or nerve-agent exposure with a compatible cholinergic syndrome.
B-035 uses salivation, tearing, urination, defecation, GI upset, emesis, and constricted pupils to describe the syndrome.
Adult / adolescent
Indication / route
Dose & limits
Respiratory distress with cholinergic findings
2 auto-injectors under the B-035 table.
Severe respiratory distress with agitation and cholinergic findings
3 auto-injectors under the B-035 table.
No signs/symptoms
Monitor for findings every 15 minutes; the table does not instruct prophylactic injection.
Pediatric
For patients younger than 12, B-035 requires a weight of at least 30 kg to receive an IM auto-injector.
For a smaller child, do not improvise a partial auto-injector dose; use the pediatric poisoning standing order and medical direction.
Pediatric dose by age / weight
B-035: weight determines eligibility in children younger than 12; clinical signs determine the number of complete devices. Do not divide an auto-injector.
Age / weight
Clinical findings
IM auto-injectors
Younger than 12 and below 30 kg
Any findings
Not eligible under B-035; pediatric poisoning pathway/base direction
Younger than 12 and at least 30 kg, or age 12–14
Respiratory distress with SLUDGEM
2 devices
Younger than 12 and at least 30 kg, or age 12–14
Severe respiratory distress, agitation, and SLUDGEM
3 devices
Eligible child; no symptoms
No respiratory distress / SLUDGEM
Monitor every 15 minutes; no prophylactic dose
Preparation & reassessment
Use the mid-anterolateral thigh. Remove the safety release, apply the injector at 90°, and hold for at least 10 seconds as specified by B-035.
Control/dispose of the exposed needle safely. Document product, time, and site; seek medical evaluation after the incident.