Field medications · Adult & pediatric guidance · ALS

Lidocaine

10-second priorities

ALS
Start here
Choose antiarrhythmic treatment OR IO-infusion analgesia.
Do not miss
IO pain control requires the specified preservative-free preparation.
Next decision
Pediatric and adult IO analgesia limits/repeats differ; do not reuse arrhythmia dosing.

Priority checkpoints. Full criteria, doses and exceptions below.

Separate antiarrhythmic dosing from preservative-free IO-infusion analgesia.

OCEMS source summary · Updated 2026-09-30

Safety sections checked September 30, 2026 · verified with limits. Existing numeric regimens retain their original source context.

Also known as: Xylocaine. NIH identifies lidocaine Xylocaine products; route, concentration, additives and intended use must match. Do not infer that every Xylocaine product is suitable for an arrhythmia or IO pain.

FIELD REFERENCE

Full criteria & treatment guidance

Indications

  • Specified ventricular-arrhythmia pathways or IO infusion pain. The indication determines dose and route.

Contraindications & local exclusions

  • The cited injection label excludes amide-local-anesthetic hypersensitivity, Stokes-Adams syndrome, Wolff-Parkinson-White syndrome, or severe sinoatrial/AV/intraventricular block without an artificial pacemaker.

Precautions

  • Monitor for neurologic toxicity, seizures, respiratory depression and conduction changes. Local anesthesia, arrhythmia treatment and IO pain use are distinct; use the exact preparation and OCEMS pathway.
  • These are selected safety checks, not a complete prescribing monograph. Product labeling and OCEMS authorization answer different questions; confirm the actual product, patient population and applicable order.

Check before giving

  • Do not interchange IO analgesia and cardiac doses.
  • Preservative-free formulation is specifically required for IO infusion analgesia in PR-115.

Use in OCEMS

  • I-15 lists lidocaine for VF/pulseless VT, wide-complex tachycardia with a pulse, and pain during IO infusion.
  • These are distinct pathways. For unstable VT with a pulse, follow the cardioversion sequence in SO-C-040.

Adult / adolescent

Adult / adolescent
Indication / routeDose & limits
Cardiac indication1 mg/kg IV/IO; may repeat 0.5 mg/kg once in 3–5 minutes under the applicable sequence.
IO infusion pain20 mg of preservative-free 2% lidocaine slowly through the IO over 1 minute. May repeat once, total 40 mg. I-15 lists a 3-minute repeat interval.

Pediatric

  • SO-P-040 persistent VF/pulseless VT: 1 mg/kg IV/IO, maximum 100 mg, one dose only, as the alternative to amiodarone in the arrest sequence.
  • PR-115 IO pain in children age 14 and younger: 0.5 mg/kg preservative-free 2% lidocaine, maximum 20 mg, slowly over 1 minute. Do not repeat.

Pediatric weight table — Persistent VF / pulseless VT

  • SO-P-040 pediatric dose: 1 mg/kg IV/IO once.
  • 1 mg/kg IV/IO, maximum 100 mg, one dose only, as the arrest alternative to amiodarone. Base contact is required under the arrest pathway.
  • This arrest regimen differs from the smaller IO-infusion pain dose.
  • Calculated examples for the exact weights shown, using the named standing-order/procedure formula. Do not round the patient’s weight to the nearest row. For another weight, calculate from the stated formula and apply the limits. These are not the rounded I-20 weight-band volumes.
  • Volumes are mathematical examples rounded to at most three decimal places. Verify the vial concentration, dose, and measurable syringe volume before administration; follow agency preparation/rounding practice.
Pediatric weight table — Persistent VF / pulseless VT
Exact weightDose — IV/IO onceVolume at 2% = 20 mg/mL
3 kg3 mg0.15 mL
4 kg4 mg0.2 mL
5 kg5 mg0.25 mL
6 kg6 mg0.3 mL
8 kg8 mg0.4 mL
10 kg10 mg0.5 mL
12 kg12 mg0.6 mL
15 kg15 mg0.75 mL
20 kg20 mg1 mL
25 kg25 mg1.25 mL
30 kg30 mg1.5 mL
35 kg35 mg1.75 mL
40 kg40 mg2 mL
45 kg45 mg2.25 mL
50 kg50 mg2.5 mL
60 kg60 mg3 mL

Pediatric weight table — IO-infusion pain

  • PR-115 pediatric dose: 0.5 mg/kg IO over 1 minute.
  • Age 14 and younger: 0.5 mg/kg preservative-free 2% lidocaine slowly over 1 minute, maximum 20 mg. Do not repeat.
  • Use only the preservative-free 2% (20 mg/mL) preparation. Follow PR-115 placement confirmation and flush instructions.
  • Calculated examples for the exact weights shown, using the named standing-order/procedure formula. Do not round the patient’s weight to the nearest row. For another weight, calculate from the stated formula and apply the limits. These are not the rounded I-20 weight-band volumes.
  • Volumes are mathematical examples rounded to at most three decimal places. Verify the vial concentration, dose, and measurable syringe volume before administration; follow agency preparation/rounding practice.
Pediatric weight table — IO-infusion pain
Exact weightDose — IO over 1 minuteVolume at Preservative-free 2% = 20 mg/mL
3 kg1.5 mg0.075 mL
4 kg2 mg0.1 mL
5 kg2.5 mg0.125 mL
6 kg3 mg0.15 mL
8 kg4 mg0.2 mL
10 kg5 mg0.25 mL
12 kg6 mg0.3 mL
15 kg7.5 mg0.375 mL
20 kg10 mg0.5 mL
25 kg12.5 mg0.625 mL
30 kg15 mg0.75 mL
35 kg17.5 mg0.875 mL
40 kg20 mg1 mL
45 kg20 mg1 mL
50 kg20 mg1 mL
60 kg20 mg1 mL

Preparation & reassessment

  • A 2% solution contains 20 mg/mL; inventory lists 100 mg/5 mL. Verify the formulation and indication.
  • Confirm IO placement and monitor the limb for extravasation. For cardiac use, reassess rhythm and perfusion and follow the full resuscitation/electrical-treatment sequence.

VISUAL FIELD REFERENCE

Lidocaine: cardiac treatment and IO analgesia differ

Adult & pediatric guidance · ALS

Adult examples. Use the separate pediatric sections for dose maximums and repeat restrictions.

  • Adult cardiac indication

    1 mg/kg IV/IO; may repeat 0.5 mg/kg once in 3–5 minutes under the applicable sequence.

  • Adult IO infusion pain

    20 mg of preservative-free 2% lidocaine slowly through the IO over 1 minute. May repeat once, total 40 mg. I-15 lists a 3-minute repeat interval.

  • Do not interchange IO analgesia and cardiac doses.
  • Preservative-free formulation is specifically required for IO infusion analgesia in PR-115.

Selected checkpoints; read the complete guide for criteria, exclusions, doses, and ongoing care. I-15 · I-20 · PR-115 · SO-C-040 · SO-P-040

UNDERSTAND THE CARE

Why one medication page contains two different treatment tasks

Lidocaine’s antiarrhythmic use and its role in pain from IO infusion are separate indications. The patient, route, dose and product requirements must be selected from the correct branch. A concentration that looks familiar does not establish that a product is appropriate for IO analgesia.

Teaching diagram: Purpose: Antiarrhythmic versus IO-infusion pain.; Product: Confirm formulation and concentration.; Regimen: Route, rate and indication-specific limits.; Record: State why it was given and the response.
Lidocaine assessment map. A teaching map of the linked guidance; it is not a complete treatment algorithm.

Applying the guidance

For rhythm treatment, retain the arrest or pulsed-tachycardia sequence and reassess perfusion. For IO pain, check the current procedure, preservative-free formulation, slow administration and adult or pediatric repeat limit. Document the reason for administration explicitly so a later clinician does not confuse pain treatment with an antiarrhythmic dose.

Dose, concentration and volume

Dose, concentration and volume. First establish the authorized dose and its cap. Read the actual concentration using consistent units. Dose divided by concentration gives volume: mg ÷ (mg/mL) = mL. Route, rate, repeat limits and authority must be checked separately.
First establish the authorized dose and its cap. Read the actual concentration using consistent units. Dose divided by concentration gives volume: mg ÷ (mg/mL) = mL. Route, rate, repeat limits and authority must be checked separately.

Diagram text & teaching checkpoints

Purpose
Antiarrhythmic versus IO-infusion pain.
Product
Confirm formulation and concentration.
Regimen
Route, rate and indication-specific limits.
Record
State why it was given and the response.

Name the indication in every handoff

A medication history of “lidocaine administered” leaves out why it was given. Make the indication explicit: antiarrhythmic treatment under its cardiac pathway, or analgesia for infusion through an IO. The same drug name does not mean the two regimens, formulation requirements or repeat limits can be combined.

For IO pain, preserve the preservative-free requirement, slow administration and age-specific limits from PR-115. Continue checking the access and surrounding extremity. A report of pain should prompt attention to the access as well as the medication record; documenting an analgesic does not establish that the site remained suitable for infusion.

For example, a child receives lidocaine for IO-infusion pain and later has an arrest-related handoff. State the original indication and amount so the next clinician does not mistake it for the arrest antiarrhythmic dose. Keep both events in the cumulative medication history without assuming that one indication authorizes another.

Source: Intraosseous Infusion.

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Related guides

Drug label / general safety

Checked September 30, 2026. Research verification is not independent clinical review.

Product labelLIDOCAINE HYDROCHLORIDE injection, solution ↗

OCEMS sources

I-15 revised March 31, 2026; I-20 revised March 26, 2026. Both implemented April 1, 2026. See linked condition-specific sources.
Source checked September 16, 2026.
Summary updated 2026-09-30.

I-15Adult / Adolescent Standing Order Drug Guide ↗I-20Pediatric Medication Volume Dose by Weight ↗PR-115Intraosseous Infusion ↗SO-C-040Wide QRS Complex Tachycardia with a Pulse - Adult/Adolescent ↗SO-P-040Cardiopulmonary Arrest - Pediatric ↗

This summary does not replace the complete policy, current system notices, or clinical judgment.

Base-contact conditions

The pediatric arrest pathway requires base contact as soon as possible. This is distinct from lidocaine for IO-infusion pain, which has no universal base-order requirement in PR-115. Other cardiac condition contact triggers remain.

Source basis: SO-P-040 explicitly marks base hospital contact required; PR-115 provides separate IO-pain regimen.

Independent OCMedic summary. Open cited source ↗ Sources, review limits & corrections

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