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Field medications · Adult & pediatric guidance · ALS

Adenosine

Regular narrow-complex tachycardia: adult treatment and pediatric base-order guidance.

OCEMS source summary · Updated 2026-09-16

Check before giving

  • Do not use for a wide, irregular rhythm.
  • PR-115 specifically identifies IO administration as ineffective for adenosine; this pathway is rapid IV.

Use in OCEMS

  • For a regular narrow-complex tachycardia with a pulse. The adult SO-C-025 pathway distinguishes mild symptoms from hemodynamic instability.
  • For mild symptoms at a rate of at least 150/min, attempt Valsalva before the medication pathway.

Adult / adolescent

Indication / routeDose & limits
Regular narrow-complex tachycardia ≥150/min12 mg rapid IV. If the rhythm persists, repeat 12 mg once after 3 minutes.
Unstable presentationFollow the synchronized-cardioversion branch of SO-C-025; do not delay urgent electrical treatment to complete a medication sequence.

Pediatric

  • I-20 marks pediatric adenosine as requiring a base hospital order. It provides separate first- and second-dose rows for each weight band.
  • Use the ordered dose and the matching weight-band chart; do not apply the adult 12 mg initial dose to a child. I-20 uses a 3 mg/mL preparation.

Pediatric weight bands — base-ordered adenosine

  • I-20 pages 1–10: base hospital order required. Rapid IV route; preparation 3 mg/mL. PR-115 states adenosine is not effective through an IO site.
  • These are the published I-20 band doses, not exact-weight calculations. Confirm the actual order and prepared volume against the linked chart; do not extrapolate outside its listed bands.
I-20 weight bandFirst dose — rapid IVSecond dose — rapid IV
3–5 kg0.4 mg0.8 mg
6–7 kg0.6 mg1.2 mg
8–9 kg0.8 mg1.6 mg
10–11 kg1 mg2 mg
12–14 kg1.2 mg2.4 mg
15–18 kg1.5 mg3 mg
19–23 kg2 mg4 mg
24–29 kg2.5 mg5 mg
30–36 kg3.5 mg7 mg
37–49 kg4.5 mg9 mg

Preparation & reassessment

  • Record the rhythm before and after administration and reassess perfusion and symptoms.
  • Confirm the actual syringe concentration and dose. A vial or syringe size is not the ordered dose.