# Dextrose 10% (D10)

Treat hypoglycemia with a titrated adult dose or measured pediatric volume.

Population: Adult & pediatric guidance. Scope: ALS.
Status: published. Source-linked OCEMS summary.
Summary updated: 2026-09-16.
Source checked: 2026-09-16.
Source version: I-15 revised March 31, 2026; I-20 revised March 26, 2026. Both implemented April 1, 2026. See linked condition-specific sources..
Canonical page: https://www.ocmedic.com/guides/dextrose/
Official source: [I-15 — Adult / Adolescent Standing Order Drug Guide](https://www.ochealthinfo.com/sites/healthcare/files/2026-04/I-15%20Adult%20SO%20Drug%20Guide%2004-2026.pdf)

Independent OC Medic summary. Does not replace the complete policy, current system notices, or clinical judgment.

## Check before giving

- D10 is 10% dextrose; do not substitute a different concentration while retaining the same volume.
- The usual IO exception requires an unconscious patient, glucose below 60, inability to obtain IV access, and no response to IM glucagon. Check the exact condition order.

## Source documents

- [I-15 — Adult / Adolescent Standing Order Drug Guide](https://www.ochealthinfo.com/sites/healthcare/files/2026-04/I-15%20Adult%20SO%20Drug%20Guide%2004-2026.pdf#page=1)
- [I-20 — Pediatric Medication Volume Dose by Weight](https://www.ochealthinfo.com/sites/healthcare/files/2026-04/I-20%20Peds%20Drug%20Guide%2004-2026.pdf)
- [PR-085 — 10% Dextrose Solution Administration](https://www.ochealthinfo.com/sites/hca/files/import/data/files/63886.pdf)
- [SO-M-020 — Altered Mental Status](https://www.ochealthinfo.com/sites/hca/files/import/data/files/12033.pdf)
- [SO-P-065 — Altered Mental Status - Pediatric](https://www.ochealthinfo.com/sites/hca/files/2021-12/SO-P-65%20Alterned%20mental%20status.pdf)
- [SO-P-075 — Seizure / Convulsion - Pediatric](https://www.ochealthinfo.com/sites/healthcare/files/2024-07/SO-P-75%20Seizures%20peds.pdf)

## Use in OCEMS

- Used for symptomatic or suspected hypoglycemia in the applicable altered-mental-status, seizure, shock, and other condition-specific pathways.
- Adult PR-085 treats glucose at or below 60 mg/dL, and permits clinical judgment in the 60–80 range when hypoglycemia is suspected. Other standing orders use their own threshold wording.

## Adult / adolescent

| Indication / route | Dose & limits |
| --- | --- |
| Hypoglycemia | D10 up to 250 mL IV, titrated to improve consciousness. Reduce to a keep-open rate when baseline mental status returns. |

## Pediatric

- SO-P-065: glucose below 60 mg/dL → D10 5 mL/kg IV, maximum 250 mL. The seizure and overdose standing orders have their own threshold wording; use the applicable source.
- PR-085 allows a measured IVPB dose or slow IV administration from a syringe. For IVPB, remove excess fluid so the bag contains only the intended pediatric dose.

## Pediatric weight table — Hypoglycemia — D10

- Source: SO-P-065. Dose rule: 5 mL/kg; route: IV.
- D10 (100 mg/mL): 5 mL/kg IV, maximum 250 mL. These values are fluid volumes of D10, not milligrams and not volumes of D50.
- For altered mental status, treat glucose below 60 mg/dL. Other pediatric standing orders have indication-specific thresholds.
- IO under SO-P-065 requires unconsciousness, glucose below 60, inability to establish IV, and no response to IM glucagon. Remove excess fluid from an IVPB bag so only the intended pediatric dose remains.
- Calculated examples for the exact weights shown, using the named standing-order/procedure formula. Do not round the patient’s weight to the nearest row. For another weight, calculate from the stated formula and apply the limits. These are not the rounded I-20 weight-band volumes.
| Exact weight | Dose — IV |
| --- | --- |
| 3 kg | 15 mL |
| 4 kg | 20 mL |
| 5 kg | 25 mL |
| 6 kg | 30 mL |
| 8 kg | 40 mL |
| 10 kg | 50 mL |
| 12 kg | 60 mL |
| 15 kg | 75 mL |
| 20 kg | 100 mL |
| 25 kg | 125 mL |
| 30 kg | 150 mL |
| 35 kg | 175 mL |
| 40 kg | 200 mL |
| 45 kg | 225 mL |
| 50 kg | 250 mL |
| 60 kg | 250 mL |

## Preparation & reassessment

- Verify glucose, weight when pediatric, concentration, and intended milliliters.
- Follow PR-085 when giving other medications through the line; flush as directed. Document glucose, mental status, administered volume, and response.